Sermorelin 2mg

Peptide Science research editorial team.

Sermorelin 2mg Overview

Sermorelin 2mg from Peptide Science is the truncated 29-amino-acid bioactive fragment of the endogenous 44-residue Growth-Hormone-Releasing Hormone (GHRH 1 to 44), supplied as a lyophilised vial for in-vitro and preclinical pituitary research. The fragment retains the GHRH-receptor binding domain and is the shortest sequence still characterised as fully active at the receptor level, which has made it the standard reference compound for hypothalamic-pituitary axis research since the 1980s.

Class and Receptor Background

Sermorelin (also designated GHRH 1-29) binds the GHRH receptor on pituitary somatotrophs and triggers adenylate cyclase activity, raising intracellular cyclic adenosine monophosphate (cAMP). The downstream cascade results in growth-hormone release from the same cell population. The 29-amino-acid format is short enough to permit cost-effective synthesis at scale while retaining the full receptor-affinity profile of the 44-residue parent hormone. Research uses include receptor-pharmacology assays, somatostatin-feedback studies, and the secretagogue-pairing protocols described in the growth-hormone peptide range.

Vial Specifications

Reconstitution and Handling

The lyophilised vial is typically reconstituted with bacteriostatic water for stability and assay-concentration studies. Pairing protocols that combine a GHRH analogue with a GHRP-class ghrelin-receptor agonist are described in the literature as the standard model for additive secretagogue research. For one such pairing in a single vial, see CJC-1295 No DAC plus GHRP-6 10mg Blend.

Quality and Shipping

Every batch passes HPLC at greater than 99 percent purity, with mass-spectrometry confirmation against the 29-amino-acid theoretical mass. A signed Certificate of Analysis ships with every order. Material is filled in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in temperature-monitored insulated packaging. For comparison work that pairs Sermorelin with the Ipamorelin pentapeptide, see Sermorelin plus Ipamorelin 10mg Blend.

For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws. Lyophilised vials store at 2 to 8 degrees Celsius; protect from light.