Peptide Science research editorial team.
Nonapeptide-1 200mg Topical Overview
Nonapeptide-1 200mg Topical from Peptide Science is the synthetic 9-amino-acid nonapeptide designed for competitive binding at the MC1R melanocortin receptor, supplied as a topical research formulation for in-vitro melanocyte cell-culture research. The compound is the INCI-designated cosmetic-research equivalent of the Melanostatin-class signal peptide family.
Compound Class and Mechanism
Nonapeptide-1 (INCI designation for the MIF-1-derived 9-residue antagonist sequence) is studied in preclinical research for competitive antagonist activity at the MC1R receptor on cultured melanocytes, blocking the downstream cyclic-AMP cascade that drives tyrosinase upregulation and melanin biosynthesis. The mechanism is upstream of the Decapeptide-12 tyrosinase competitive inhibition pathway, providing a complementary research tool for pigmentation-pathway studies. Browse the broader cosmetic peptide range.
Specifications
| Property | Value |
|---|---|
| Compound | Nonapeptide-1 (sequence Met-Pro-Phe-Arg-Tyr-Pro-Leu-Leu-NH2) |
| Class | Synthetic alpha-MSH antagonist nonapeptide; melanocyte-pathway signal peptide |
| Amino-acid count | 9 |
| Molecular weight | approximately 1156 g/mol |
| Source-protein basis | Melanocyte-inhibiting factor (MIF-1)-derived synthetic 9-residue analog |
| Supplied form | Topical research formulation |
| Strength | 200 mg per supply |
| Purity | greater than 99 percent (HPLC verified) |
| Storage | 2 to 8 degrees Celsius; protect from light |
For the related Melanostatin DM form of the same family, see Melanostatin DM 200mg Topical.
Handling and Stability
The research-grade supply is intended for in-vitro cell-culture and preclinical animal-model work. The working concentration used in any given research protocol is set by the principal investigator.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation. A Certificate of Analysis accompanies every order. Material is prepared in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in temperature-monitored packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.
Reviews
There are no reviews yet.