Peptide Science research editorial team.
Matrixyl 200mg Topical Overview
Matrixyl 200mg Topical from Peptide Science is the synthetic palmitoylated pentapeptide derived from the C-terminal pro-peptide fragment of human type I procollagen, supplied as a topical research formulation for in-vitro fibroblast and collagen-pathway research. Matrixyl is one of the most-cited signal peptides in published cosmetic-research literature.
Compound Class and Mechanism
Matrixyl is the C16 fatty-acid-conjugated form of the KTTKS sequence (Lys-Thr-Thr-Lys-Ser), a 5-residue fragment of the C-terminal pro-peptide of human type I procollagen. The palmitoyl conjugation improves lipophilicity and skin-cell penetration relative to the free pentapeptide. Preclinical research has characterised the molecule for stimulation of collagen, fibronectin, and glycosaminoglycan synthesis in cultured fibroblasts, with reported downstream effects on extracellular matrix remodeling pathways. Browse the broader cosmetic peptide range for related signal peptides studied in dermal-cell research.
Specifications
| Property | Value |
|---|---|
| Compound | Matrixyl (Palmitoyl Pentapeptide-4, also designated KTTKS) |
| Class | Synthetic palmitoylated pentapeptide; collagen-fragment signal peptide |
| Amino-acid count | 5 |
| Molecular weight | approximately 802.1 g/mol |
| Source-protein basis | Type I procollagen C-terminal pro-peptide fragment |
| Supplied form | Topical research formulation |
| Strength | 200 mg per supply |
| Purity | greater than 99 percent (HPLC verified) |
| Storage | 2 to 8 degrees Celsius; protect from light |
For paired research with the related palmitoylated tripeptide and tetrapeptide cosmetic signal peptides, see Pal-GHK 200mg Topical, Syn-Coll 200mg Topical, and Rigin 200mg Topical.
Handling and Reconstitution
The topical research formulation is supplied for in-vitro cell-culture and animal-model dermatology work, not as a finished cosmetic product. The working concentration used in any given research protocol is set by the principal investigator. Aliquoting reconstituted stock for single-use storage is the standard handling practice for short signal peptides where repeated freeze-thaw cycles can affect activity.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation. A Certificate of Analysis accompanies every order. Material is prepared in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in insulated, light-protected packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.
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