Peptide Science research editorial team.
Pal-GHK 200mg (Palmitoyl Tripeptide-1) Topical Overview
Pal-GHK 200mg (Palmitoyl Tripeptide-1) Topical from Peptide Science is the synthetic palmitoylated form of the glycyl-L-histidyl-L-lysine tripeptide, supplied as a topical research formulation for in-vitro fibroblast and collagen-pathway research. The C16 fatty-acid conjugation increases lipophilicity and dermal-cell penetration relative to the free GHK or copper-bound GHK-Cu forms.
Compound Class and Mechanism
Pal-GHK is the palmitoyl-conjugated form of the naturally occurring Gly-His-Lys tripeptide present in human plasma. The N-terminal palmitoylation extends the peptide’s lipophilic profile for skin-cell research without copper coordination, distinguishing it from the copper-bound GHK-Cu form sold separately in this catalogue. Preclinical cell-culture studies have characterised Pal-GHK for effects on collagen synthesis, fibroblast activity, and extracellular matrix protein expression in dermal-cell research. Browse the broader cosmetic peptide range for related signal peptides studied in dermal-cell research.
Specifications
| Property | Value |
|---|---|
| Compound | Pal-GHK (Palmitoyl Tripeptide-1, sequence Pal-Gly-His-Lys) |
| Class | Synthetic palmitoylated copper-binding tripeptide; collagen-pathway signal peptide |
| Amino-acid count | 3 |
| Molecular weight | approximately 578.8 g/mol |
| Source-protein basis | Human plasma GHK tripeptide (palmitoyl-conjugated form) |
| Supplied form | Topical research formulation |
| Strength | 200 mg per supply |
| Purity | greater than 99 percent (HPLC verified) |
| Storage | 2 to 8 degrees Celsius; protect from light |
For the copper-bound form of the same tripeptide sequence, see GHK-Cu 200mg Topical. For the related palmitoylated pentapeptide collagen-fragment signal peptide, see Matrixyl 200mg Topical.
Handling and Reconstitution
The topical research formulation is supplied for in-vitro cell-culture and animal-model dermatology work, not as a finished cosmetic product. The working concentration used in any given research protocol is set by the principal investigator. Aliquoting reconstituted stock for single-use storage is the standard handling practice for short signal peptides where repeated freeze-thaw cycles can affect activity.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation. A Certificate of Analysis accompanies every order. Material is prepared in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in insulated, light-protected packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.
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