Peptide Science research editorial team.
B7-33 (Relaxin Analog) 6mg Overview
B7-33 (Relaxin Analog) 6mg from Peptide Science is the synthetic 27-amino-acid single-chain relaxin-2 analog, supplied as a lyophilised vial for in-vitro and preclinical cardiovascular and fibrosis-pathway research. The compound corresponds to residues 7 through 33 of the B chain of native human relaxin-2 in a single-chain format that retains receptor activity without the disulfide-linked A chain of native relaxin.
Compound Class and Mechanism
B7-33 has been characterised in preclinical research for agonist activity at the relaxin family peptide receptor 1 (RXFP1), the cognate receptor for native relaxin-2. The single-chain format gives the analog distinct cell-culture pharmacology from the disulfide-linked native two-chain relaxin, with reported preference for the ERK1/2 signalling pathway downstream of RXFP1 over the cAMP-pathway preferred by native relaxin. The compound is studied as a research tool for biased-agonism investigations at the RXFP1 receptor and for cardiac and renal fibrosis-pathway models. Browse the broader healing peptide range.
Specifications
| Property | Value |
|---|---|
| Compound | B7-33 (single-chain relaxin analog, B-chain residues 7 to 33) |
| Class | Synthetic single-chain relaxin-2 analog; RXFP1 receptor agonist |
| Amino-acid count | 27 |
| Molecular weight | approximately 3146 g/mol |
| Supplied form | Lyophilised powder, sealed vial |
| Strength | 6 mg per vial |
| Purity | greater than 99 percent (HPLC verified) |
| Storage | 2 to 8 degrees Celsius lyophilised; minus 20 degrees Celsius long-term |
For paired research with cardiovascular bioregulator peptides, see Cardiogen 20mg or Vesugen 20mg.
Reconstitution and Handling
The lyophilised vial reconstitutes with bacteriostatic water at the working concentration set by the principal investigator. Aliquoting reconstituted stock for single-use frozen storage is the standard preclinical handling practice for short-sequence peptides.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation. A Certificate of Analysis accompanies every order. Material is filled in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in temperature-monitored insulated packaging.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.
Reviews
There are no reviews yet.