Peptide Science research editorial team.
Follistatin 344 1mg Overview
Follistatin 344 1mg from Peptide Science is the synthetic 344-residue alternative splice isoform of human follistatin, supplied as a lyophilised vial for in-vitro myostatin-pathway and preclinical muscle-research applications. Follistatin 344 is the secreted longer isoform with extracellular activity, distinct from the cell-surface-associated Follistatin 315.
Compound Class and Mechanism
Follistatin is a glycoprotein that binds and neutralises members of the transforming growth factor beta superfamily, most prominently activin A, activin B, and myostatin (GDF-8). The 344-residue isoform (FST-344) is the secreted form found in extracellular fluid and circulating plasma, distinguishing it from the 315-residue cell-surface form. Preclinical research has characterised follistatin for blockade of myostatin’s negative-regulator effect on muscle-cell growth, supporting research models on satellite-cell proliferation and muscle-mass pathways. Browse the broader IGF and muscle-growth peptide range.
Specifications
| Property | Value |
|---|---|
| Compound | Follistatin 344 (FST-344, 344-residue alternative splice isoform of human follistatin) |
| Class | Myostatin-binding glycoprotein; activin and myostatin neutraliser research compound |
| Amino-acid count | 344 |
| Molecular weight | approximately 37820 g/mol |
| Supplied form | Lyophilised powder, sealed vial |
| Strength | 1 mg per vial |
| Purity | greater than 99 percent (HPLC verified) |
| Storage | 2 to 8 degrees Celsius lyophilised; minus 20 degrees Celsius long-term |
For the cell-surface-associated 315-residue isoform, see Follistatin 315 1mg.
Reconstitution and Handling
The lyophilised vial reconstitutes with bacteriostatic water at the working concentration set by the principal investigator. Aliquoting reconstituted stock for single-use frozen storage is the standard preclinical handling practice cited in peptide-research literature.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation. A Certificate of Analysis accompanies every order. Material is filled in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in temperature-monitored insulated packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.
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