Peptide Science research editorial team.
PEG MGF 5mg Overview
PEG MGF 5mg from Peptide Science is the polyethylene-glycol-conjugated form of the 24-amino-acid Mechano Growth Factor (MGF) peptide, supplied as a lyophilised vial for in-vitro myogenesis and preclinical satellite-cell research. The PEG conjugation extends the in-vitro half-life relative to the unconjugated MGF parent peptide.
Compound Class and Mechanism
PEG-MGF is the polyethylene-glycol (typically ~5 kilodalton PEG) conjugated form of the 24-amino-acid C-terminal portion of the IGF-1Ec splice variant. The PEG moiety increases the hydrodynamic radius of the molecule, slowing renal clearance and proteolytic degradation in cell-culture stability studies. The active MGF sequence retains its characterised role in satellite-cell activation and proliferation effects in damaged muscle tissue research, with the PEG conjugation extending the assay window for longer-duration cell-culture protocols. Browse the broader IGF and muscle-growth peptide range.
Specifications
| Property | Value |
|---|---|
| Compound | PEG-MGF (PEGylated Mechano Growth Factor) |
| Class | PEGylated IGF-1Ec splice variant; long-acting MGF analog |
| Amino-acid count | 24 |
| Molecular weight | approximately 7867 g/mol |
| Supplied form | Lyophilised powder, sealed vial |
| Strength | 5 mg per vial |
| Purity | greater than 99 percent (HPLC verified) |
| Storage | 2 to 8 degrees Celsius lyophilised; minus 20 degrees Celsius long-term |
For the unconjugated parent MGF peptide, see MGF Peptide (IGF-1 Ec) 5mg.
Reconstitution and Handling
The lyophilised vial reconstitutes with bacteriostatic water at the working concentration set by the principal investigator. Aliquoting reconstituted stock for single-use frozen storage is the standard preclinical handling practice cited in peptide-research literature.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation. A Certificate of Analysis accompanies every order. Material is filled in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in temperature-monitored insulated packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.
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