Peptide Science research editorial team.
MK-677 (Ibutamoren) 12.5mg 60-Capsule Overview
MK-677 (Ibutamoren) 12.5mg 60-Capsule from Peptide Science is the encapsulated oral-format research preparation of the orally-active small-molecule ghrelin-receptor agonist, supplied at 12.5 milligrams per capsule in a 60-count sealed bottle for preclinical animal-model research on the GH and IGF-1 axis.
Class and Mechanism in Preclinical Research
MK-677 (Ibutamoren mesylate) is a non-peptide small-molecule agonist of the growth-hormone secretagogue receptor (GHS-R1a), distinguished from the peptide GHRP-class compounds by its oral bioavailability and extended plasma half-life. Preclinical research has characterised the compound for sustained activation of the ghrelin-receptor pathway in cell-culture and animal-model studies, with reported downstream effects on growth hormone and IGF-1 axis activity over multi-day administration periods. The compound is sometimes mis-classified as a SARM in lay sources, which is incorrect: MK-677 has no androgen-receptor activity. Browse the broader growth-hormone peptide range for related research material.
Per-Capsule Specifications
| Property | Value |
|---|---|
| Compound | MK-677 (Ibutamoren mesylate) |
| Class | Non-peptide small-molecule ghrelin-receptor agonist (GHS-R1a) |
| Molecular weight | approximately 624.8 g/mol (mesylate salt) |
| Strength per capsule | 12.5 mg |
| Pack count | 60 capsules per bottle |
| Supplied form | Gelatin capsule, sealed bottle |
| Purity | greater than 99 percent (HPLC-MS verified) |
| Storage | Room temperature, sealed, dry; avoid direct sunlight and humidity |
Handling and Stability
The sealed bottle stores at room temperature in a dry environment, away from direct sunlight and humidity. For comparison studies with the injectable peptide ghrelin-receptor agonist class, see Ipamorelin 5mg or GHRP-2 5mg.
Quality and Shipping
Each batch passes HPLC and mass spectrometry at greater than 99 percent purity. A Certificate of Analysis accompanies every order. Material is prepared in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in standard sealed packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws. Lyophilised vials store at 2 to 8 degrees Celsius; protect from light.





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