Peptide Science research editorial team.
TB-500 5mg Full-Length Profile
TB-500 5mg from Peptide Science is the 5 mg lyophilised vial of the full 43-amino-acid Thymosin Beta-4 protein, the complete native sequence of the actin-sequestering protein. The 5 mg pack covers most standard cell-culture experimental arms in regenerative-research protocols requiring the complete protein rather than the 7-amino-acid active fragment.
Beta-Thymosin Background
Thymosin Beta-4 is the most abundant beta-thymosin in mammalian cells and is characterised for one-to-one binding of monomeric G-actin via its actin-binding KLKKTET motif. The protein is studied in preclinical research for its role in actin cytoskeleton dynamics, cell migration, angiogenesis, and tissue repair. The full 43-residue form differs in activity profile from the truncated TB-500 17 to 23 fragment, which is why both versions appear in this catalogue. See the broader healing peptide range.
At-a-Glance Specifications
| Property | Value |
|---|---|
| Compound | Thymosin Beta-4 full 43-amino-acid protein |
| Amino-acid count | 43 |
| Molecular weight | approximately 4960 g/mol |
| Actin-binding motif | KLKKTET (residues 17 to 23) |
| Class | Beta-thymosin family; actin-sequestering protein |
| Supplied form | Lyophilised powder, sealed vial |
| Strength | 5 mg per vial |
| Purity | greater than 99 percent (HPLC verified) |
| Storage | 2 to 8 degrees Celsius lyophilised; minus 20 degrees Celsius long-term |
For the 2 mg and 10 mg single-vial formats of the same full-length protein, see TB-500 2mg.
Reconstitution and Handling
The lyophilised full-length protein reconstitutes with bacteriostatic water for cell-culture or animal-model work. For research protocols that use only the active actin-binding fragment, see TB-500 Fragment 17-23 10mg.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spec confirmation against the 4960 g/mol theoretical molecular weight. A Certificate of Analysis accompanies every order. Material is filled in a US laboratory and dispatched in insulated, temperature-monitored packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws. Lyophilised vials store at 2 to 8 degrees Celsius; protect from light.
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