AICAR 50mg is a research vial of 5-aminoimidazole-4-carboxamide ribonucleotide from Peptide Sciences, used to study AMPK activation.
AICAR Research Overview
AICAR is converted inside cells to ZMP, an AMP mimic that activates AMP-activated protein kinase (AMPK), the cell’s central energy sensor. Research uses it to study glucose uptake, fatty-acid oxidation and mitochondrial biogenesis, and it was among the first compounds described as an exercise mimetic in mouse studies.
AICAR 50mg Specifications
| Property | Value |
|---|---|
| Compound | AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) |
| Class | Adenosine analog; AMPK-activator research compound |
| Amino-acid count | n/a |
| Molecular weight | approximately 338.2 g/mol |
| Supplied form | Lyophilised powder, sealed vial |
| Strength | 50 mg per vial |
| Purity | greater than 99 percent (HPLC and mass-spec verified) |
| Storage | Room temperature, sealed, dry; long-term storage at minus 20 degrees Celsius |
Using the 50mg Vial
Suitable for cell and animal metabolism studies, often compared with MOTS-c and SLU-PP-332.
Research Considerations
AICAR studies frequently measure phosphorylated AMPK and ACC in muscle and liver, along with endurance performance in rodent treadmill tests.
Quality Control, COA and Shipping
Quality documentation matters for reproducible research. Every vial is traceable to a lot number, every lot carries an HPLC chromatogram and mass-spectrometry report, and orders are dispatched quickly from the USA in discreet, temperature-protected packaging.
Related Research Compounds
Researchers working with AICAR often compare results with these catalog compounds:
Explore the full Anti Aging Peptides collection, browse the complete Peptide Sciences research peptide catalog, or review published literature on AICAR in PubMed.
Research use only. This product is sold strictly for in-vitro laboratory research and development by qualified professionals. It is not for human or veterinary use, not a drug, food or cosmetic, and has not been evaluated by the FDA to diagnose, treat, cure or prevent any disease. Buyers must be 21+ and comply with all applicable laws.





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