MOTS-c 5mg is a research vial of the 16-amino-acid mitochondrial-derived peptide from Peptide Sciences, used in metabolic and ageing research.
MOTS-c Research Overview
MOTS-c is encoded within the mitochondrial 12S rRNA gene, an unusual origin for a signalling peptide. Studies in mice link it to AMPK activation, improved insulin sensitivity, exercise capacity and resistance to diet-induced obesity. It can move to the nucleus under stress, where it influences gene expression.
MOTS-c 5mg Specifications
| Property | Value |
|---|---|
| Compound | MOTS-c (Mitochondrial Open Reading frame of the Twelve S rRNA-c) |
| Class | Mitochondrial-derived peptide (MDP) |
| Amino-acid count | 16 |
| Molecular weight | approximately 2174 g/mol |
| Supplied form | Lyophilised powder, sealed vial |
| Strength | 5 mg per vial |
| Purity | greater than 99 percent (HPLC and mass-spec verified) |
| Storage | 2 to 8 degrees Celsius lyophilised; minus 20 degrees Celsius long-term |
Using the 5mg Vial
Ideal for pilot and cell studies. The 10mg vial suits larger programmes.
Research Considerations
Metabolic studies with MOTS-c frequently measure AMPK phosphorylation, glucose uptake in skeletal muscle and whole-body energy expenditure in diet-induced obesity models.
Quality Control, COA and Shipping
Consistency between lots is checked by HPLC and mass spectrometry, so researchers can compare results across experiments with confidence. Each order ships with a lot-specific Certificate of Analysis and cold-chain packaging.
Related Research Compounds
Researchers working with MOTS-c often compare results with these catalog compounds:
Explore the full Anti Aging Peptides collection, browse the complete Peptide Sciences research peptide catalog, or review published literature on MOTS-c in PubMed.
Research use only. This product is sold strictly for in-vitro laboratory research and development by qualified professionals. It is not for human or veterinary use, not a drug, food or cosmetic, and has not been evaluated by the FDA to diagnose, treat, cure or prevent any disease. Buyers must be 21+ and comply with all applicable laws.









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