Peptide Science research editorial team.
MOTS-c 5mg Overview
MOTS-c 5mg from Peptide Science is the standard single-vial format of the 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S ribosomal RNA gene, supplied as a lyophilised powder for in-vitro and preclinical bioenergetic and metabolic research. The 5 mg pack covers standard cell-culture experimental arms in MOTS-c pathway studies.
Compound Class and Mechanism
MOTS-c (Mitochondrial Open Reading frame of the Twelve S rRNA-c) is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S ribosomal RNA gene. The peptide has been characterised in preclinical research as a mitochondrial-genome-encoded signalling molecule with reported effects on insulin sensitivity, AMP-activated protein kinase (AMPK) pathway activation, and metabolic homeostasis in cell-culture and animal-model studies. MOTS-c is one of the small but growing family of characterised mitochondrial-derived peptides alongside Humanin and SHLP1-6.
Specifications
| Property | Value |
|---|---|
| Compound | MOTS-c (Mitochondrial Open Reading frame of the Twelve S rRNA-c) |
| Class | Mitochondrial-derived peptide (MDP) |
| Amino-acid count | 16 |
| Molecular weight | approximately 2174 g/mol |
| Supplied form | Lyophilised powder, sealed vial |
| Strength | 5 mg per vial |
| Purity | greater than 99 percent (HPLC and mass-spec verified) |
| Storage | 2 to 8 degrees Celsius lyophilised; minus 20 degrees Celsius long-term |
For the higher-strength 10 mg single-vial format, see MOTS-c 10mg. For paired research with another mitochondrial-derived peptide, see Humanin 10mg.
Reconstitution and Handling
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Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation against the theoretical molecular weight. A Certificate of Analysis accompanies every order. Material is filled in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in temperature-monitored insulated packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws. Lyophilised vials store at 2 to 8 degrees Celsius; protect from light.
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