Peptide Science research editorial team.
N-Acetyl Epithalon Amidate 20mg Overview
N-Acetyl Epithalon Amidate 20mg from Peptide Science is the stability-enhanced analog of the parent Epithalon pineal tetrapeptide, with N-terminal acetylation and C-terminal amidation modifications that increase resistance to enzymatic degradation by aminopeptidases and carboxypeptidases. The modified form is supplied as a lyophilised vial for extended in-vitro telomerase-activation research where the parent peptide’s short half-life limits assay window length.
Compound Class and Mechanism
The base Epithalon sequence (Ala-Glu-Asp-Gly) is the pineal tetrapeptide characterised in preclinical research for telomerase-enzyme activation in cell-culture models. N-terminal acetylation blocks the free amino group attacked by aminopeptidases, and C-terminal amidation blocks the carboxyl-terminal cleavage site. The modified analog retains the receptor / target-binding activity of the parent tetrapeptide while extending the in-vitro half-life by an order of magnitude or more in cell-culture conditions. Browse the broader anti-aging peptide range.
Specifications
| Property | Value |
|---|---|
| Compound | N-Acetyl Epithalon Amidate |
| Class | Stability-modified Epithalon analog; Khavinson short-peptide family |
| Amino-acid count | 4 |
| Molecular weight | approximately 431 g/mol |
| Supplied form | Lyophilised powder, sealed vial |
| Strength | 20 mg per vial |
| Purity | greater than 99 percent (HPLC and mass-spec verified) |
| Storage | 2 to 8 degrees Celsius lyophilised; minus 20 degrees Celsius long-term |
For the unmodified parent peptide, see Epithalon (Epitalon) 20mg.
Reconstitution and Handling
The lyophilised vial reconstitutes with bacteriostatic water at the working concentration set by the principal investigator. Aliquoting reconstituted stock for single-use frozen storage is the standard preclinical handling practice cited in peptide-research literature.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation against the theoretical molecular weight. A Certificate of Analysis accompanies every order. Material is filled in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in temperature-monitored insulated packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.
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