Peptide Science research editorial team.
Epithalon 20mg Overview
Epithalon (Epitalon) 20mg from Peptide Science is a synthetic pineal tetrapeptide with the sequence Ala-Glu-Asp-Gly, supplied as a lyophilised vial for in-vitro telomerase-activation and preclinical longevity research. The compound was originally isolated from bovine pineal extract by V. Kh. Khavinson and colleagues in the 1990s, and the 20 mg strength format supports multi-experiment cell-culture series at a working stock that reduces vial-opening frequency.
Class and Mechanism in Longevity Research
Epithalon belongs to the Khavinson short-peptide class, a family of synthetic two-to-four-residue peptides derived from bioregulator-fraction studies of mammalian tissues. The tetrapeptide has been characterised in cell-culture work for telomerase-enzyme activation and downstream effects on telomere-length maintenance. Reported preclinical mechanisms include modulation of pineal-gland melatonin synthesis and effects on circadian-gene expression in animal models. Browse related compounds in the anti-aging peptide range.
Specifications
| Property | Value |
|---|---|
| Compound | Epithalon (Epitalon) |
| Sequence | Ala-Glu-Asp-Gly |
| Amino-acid count | 4 |
| Molecular weight | approximately 390.4 g/mol |
| Class | Pineal tetrapeptide, Khavinson short-peptide family |
| Supplied form | Lyophilised powder, sealed vial |
| Strength | 20 mg per vial |
| Purity | greater than 99 percent (HPLC and mass-spec verified) |
| Storage | 2 to 8 degrees Celsius lyophilised; minus 20 degrees Celsius long-term |
For the stability-modified analogue with acetyl and amidate end groups, see N-Acetyl Epitalon Amidate 20mg.
Reconstitution and Handling
The lyophilised tetrapeptide is typically reconstituted with bacteriostatic water for cell-culture work. The pineal-derived bioregulator class is often studied alongside nootropic short peptides such as Pinealon and Cortexin, both of which sit in related Khavinson research lineages. For the higher-strength 50 mg format suited to extended studies, see Epithalon (Epitalon) 50mg.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry confirmation against the theoretical 390.4 g/mol tetrapeptide mass. A signed Certificate of Analysis ships with every order. Material is filled in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in insulated, temperature-monitored packaging. For paired research that compares tetrapeptide telomerase signals with bioenergetic-pathway compounds, see the Longevity and Obesity Research 60-capsule blend covering 5-Amino-1MQ, NMN, and JBSNF.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws. Lyophilised vials store at 2 to 8 degrees Celsius; protect from light.





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