Peptide Science research editorial team.
Humanin 10mg Overview
Humanin 10mg from Peptide Science is the synthetic 24-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 16S ribosomal RNA gene, supplied as a lyophilised vial for in-vitro neuroprotection and preclinical apoptosis research. Humanin is one of the small family of characterised mitochondrial-derived peptides alongside MOTS-c and the SHLP1-6 series.
Compound Class and Mechanism
Humanin (sequence MAPRGFSCLLLLTSEIDLPVKRRA) was originally identified in research on Alzheimer’s-disease-affected brain tissue and has been characterised in preclinical work for binding interactions with the pro-apoptotic protein Bax and the IGFBP-3 binding protein. Reported activity in cell-culture models includes inhibition of apoptosis in neurons and cardiomyocytes, and effects on glucose metabolism via cell-membrane receptor pathways. Browse the broader anti-aging peptide range.
Specifications
| Property | Value |
|---|---|
| Compound | Humanin |
| Class | Mitochondrial-derived peptide (MDP) |
| Amino-acid count | 24 |
| Molecular weight | approximately 2687 g/mol |
| Supplied form | Lyophilised powder, sealed vial |
| Strength | 10 mg per vial |
| Purity | greater than 99 percent (HPLC and mass-spec verified) |
| Storage | 2 to 8 degrees Celsius lyophilised; minus 20 degrees Celsius long-term |
For paired research with the other characterised mitochondrial-derived peptide, see MOTS-c 10mg.
Reconstitution and Handling
The lyophilised vial reconstitutes with bacteriostatic water at the working concentration set by the principal investigator. Aliquoting reconstituted stock for single-use frozen storage is the standard preclinical handling practice cited in peptide-research literature.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation against the theoretical molecular weight. A Certificate of Analysis accompanies every order. Material is filled in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in temperature-monitored insulated packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.
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