Peptide Science research editorial team.
Pal-AHK 200mg Topical Overview
Pal-AHK 200mg Topical from Peptide Science is the synthetic palmitoylated form of the alanyl-L-histidyl-L-lysine tripeptide, supplied as a topical research formulation for in-vitro hair-follicle and dermal-papilla cell research. The compound is the alanine-substituted analog of the Pal-GHK tripeptide, with the N-terminal glycine replaced by alanine.
Compound Class and Mechanism
Pal-AHK retains the histidine and lysine residues that give the parent AHK family its copper-coordination affinity (analogous to GHK), with the N-terminal alanine substitution providing distinct cell-culture activity from the parent GHK and Pal-GHK forms. The palmitoyl conjugation increases lipophilicity for dermal-cell research. Preclinical cell-culture work has characterised the molecule for effects on hair-follicle cell signalling and dermal-papilla cell-culture models. Browse the broader cosmetic peptide range for related signal peptides studied in dermal-cell research.
Specifications
| Property | Value |
|---|---|
| Compound | Pal-AHK (Palmitoyl Tripeptide-3, sequence Pal-Ala-His-Lys) |
| Class | Synthetic palmitoylated copper-affinity tripeptide; hair-research signal peptide |
| Amino-acid count | 3 |
| Molecular weight | approximately 552.8 g/mol |
| Source-protein basis | AHK tripeptide (alanine-substituted GHK analog, palmitoyl-conjugated) |
| Supplied form | Topical research formulation |
| Strength | 200 mg per supply |
| Purity | greater than 99 percent (HPLC verified) |
| Storage | 2 to 8 degrees Celsius; protect from light |
For the related copper-bound AHK form, see AHK-Cu Copper Tripeptide 200mg Topical. For the structurally similar Pal-GHK, see Pal-GHK 200mg Topical.
Handling and Reconstitution
The topical research formulation is supplied for in-vitro cell-culture and animal-model dermatology work, not as a finished cosmetic product. The working concentration used in any given research protocol is set by the principal investigator. Aliquoting reconstituted stock for single-use storage is the standard handling practice for short signal peptides where repeated freeze-thaw cycles can affect activity.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation. A Certificate of Analysis accompanies every order. Material is prepared in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in insulated, light-protected packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.
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