Peptide Science research editorial team.
Melanostatin DM 200mg Topical Overview
Melanostatin DM 200mg Topical from Peptide Science is the synthetic 9-amino-acid nonapeptide designed as a competitive antagonist of the alpha-melanocyte-stimulating hormone (alpha-MSH) receptor pathway, supplied as a topical research formulation for in-vitro melanocyte and pigmentation-pathway research.
Compound Class and Mechanism
Melanostatin DM is structurally derived from the melanocyte-inhibiting factor family of peptides, designed to competitively bind the MC1R melanocortin receptor on melanocytes without triggering downstream melanin-biosynthesis signalling. The compound has been characterised in preclinical cell-culture research for melanocyte pathway inhibition, distinct mechanistically from the tyrosinase competitive inhibitor Decapeptide-12 also in this catalogue. Browse the broader cosmetic peptide range.
Specifications
| Property | Value |
|---|---|
| Compound | Melanostatin DM (Nonapeptide-1, sequence Met-Pro-Phe-Arg-Tyr-Pro-Leu-Leu-NH2) |
| Class | Synthetic alpha-MSH antagonist nonapeptide; melanocyte-pathway signal peptide |
| Amino-acid count | 9 |
| Molecular weight | approximately 1156 g/mol |
| Source-protein basis | Melanocyte-inhibiting factor (MIF-1)-derived synthetic analog |
| Supplied form | Topical research formulation |
| Strength | 200 mg per supply |
| Purity | greater than 99 percent (HPLC verified) |
| Storage | 2 to 8 degrees Celsius; protect from light |
For the alternative pigmentation-pathway research peptide that targets tyrosinase rather than the MC1R receptor, see Decapeptide-12 200mg Topical.
Handling and Stability
The research-grade supply is intended for in-vitro cell-culture and preclinical animal-model work. The working concentration used in any given research protocol is set by the principal investigator.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation. A Certificate of Analysis accompanies every order. Material is prepared in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in temperature-monitored packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.





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