Peptide Science research editorial team.
SNAP-8 200mg Topical Overview
SNAP-8 200mg Topical from Peptide Science is the synthetic 8-amino-acid signal peptide extending the Argireline (Acetyl Hexapeptide) sequence by two additional residues at the C-terminus, supplied as a topical research formulation for in-vitro SNARE-complex research. The extended sequence provides a longer SNAP-25 N-terminal mimic than the 6-residue Argireline parent.
Compound Class and Mechanism
SNAP-8 is the acetylated 8-residue N-terminal extension of the SNAP-25 protein sequence, structurally adding Ala-Asp at the C-terminus of the parent Argireline hexapeptide. Like Argireline, the peptide has been characterised in preclinical research for competitive inhibition of SNARE-complex assembly via N-terminal SNAP-25 mimicry, which is the structural basis for its study in dermal-cell research on neurotransmitter-release pathways. Browse the broader cosmetic peptide range for related signal peptides studied in dermal-cell research.
Specifications
| Property | Value |
|---|---|
| Compound | SNAP-8 (Acetyl Glutamyl Octapeptide-3, sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp) |
| Class | Synthetic SNARE-complex signal peptide; Argireline 8-residue analog |
| Amino-acid count | 8 |
| Molecular weight | approximately 1075 g/mol |
| Source-protein basis | SNAP-25 N-terminal fragment (extended Argireline 8-residue analog) |
| Supplied form | Topical research formulation |
| Strength | 200 mg per supply |
| Purity | greater than 99 percent (HPLC verified) |
| Storage | 2 to 8 degrees Celsius; protect from light |
For the parent 6-residue Argireline, see Argireline 200mg Topical. For the related enkephalin-derived signal peptide, see Leuphasyl 200mg Topical.
Handling and Reconstitution
The topical research formulation is supplied for in-vitro cell-culture and animal-model dermatology work, not as a finished cosmetic product. The working concentration used in any given research protocol is set by the principal investigator. Aliquoting reconstituted stock for single-use storage is the standard handling practice for short signal peptides where repeated freeze-thaw cycles can affect activity.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation. A Certificate of Analysis accompanies every order. Material is prepared in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in insulated, light-protected packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.
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