Peptide Science research editorial team.
Syn-AKE 200mg Topical Overview
Syn-AKE 200mg Topical from Peptide Science is the synthetic dipeptide mimic of the waglerin-1 snake-venom peptide, supplied as a topical research formulation for in-vitro neuromuscular-junction and dermal cell-culture work. The compound is the 2-residue functional mimic of the much larger 22-amino-acid waglerin-1 from Tropidolaemus wagleri venom.
Compound Class and Mechanism
Syn-AKE (dipeptide diaminobutyroyl benzylamide diacetate) is a small-molecule mimic of the muscle-type nicotinic acetylcholine receptor antagonist waglerin-1. The compound has been characterised in preclinical research for competitive inhibition at the postsynaptic nicotinic receptor, with reported downstream effects on acetylcholine-mediated muscle-cell contraction in cell-culture models. The dipeptide mimic provides waglerin-1-like activity in a much smaller molecule suited to cosmetic-research formulation work. Browse the broader cosmetic peptide range for related signal peptides studied in dermal-cell research.
Specifications
| Property | Value |
|---|---|
| Compound | Syn-AKE (Dipeptide diaminobutyroyl benzylamide diacetate) |
| Class | Synthetic dipeptide mimic of waglerin-1; nicotinic-receptor signal peptide |
| Amino-acid count | 2 |
| Molecular weight | approximately 514.6 g/mol |
| Source-protein basis | Waglerin-1 snake-venom peptide (synthetic dipeptide mimic) |
| Supplied form | Topical research formulation |
| Strength | 200 mg per supply |
| Purity | greater than 99 percent (HPLC verified) |
| Storage | 2 to 8 degrees Celsius; protect from light |
For related dermal signal peptides studied alongside Syn-AKE in neuromuscular-junction-adjacent research, see Argireline 200mg Topical.
Handling and Reconstitution
The topical research formulation is supplied for in-vitro cell-culture and animal-model dermatology work, not as a finished cosmetic product. The working concentration used in any given research protocol is set by the principal investigator. Aliquoting reconstituted stock for single-use storage is the standard handling practice for short signal peptides where repeated freeze-thaw cycles can affect activity.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation. A Certificate of Analysis accompanies every order. Material is prepared in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in insulated, light-protected packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.
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