Peptide Science research editorial team.
ARA-290 Peptide 16mg Overview
ARA-290 Peptide 16mg from Peptide Science is the synthetic 11-amino-acid peptide derived from helix B of human erythropoietin (EPO), supplied as a lyophilised vial for in-vitro and preclinical innate-repair-pathway research. ARA-290 (also designated Cibinetide) is one of the most-cited tissue-protective members of the EPO-derived peptide class.
Compound Class and Mechanism
ARA-290 corresponds to the 11-residue B-helix surface sequence of erythropoietin and selectively activates the heteromeric innate repair receptor (IRR, also called the tissue-protective receptor), a complex of the EPO receptor with the common beta-receptor of the GM-CSF / IL-3 / IL-5 family. The compound has been characterised in preclinical research for tissue-protective signalling without the erythropoietic activity of the parent EPO, which is the structural basis for its use as a research tool for separating the tissue-protective from the haematopoietic effects of EPO. Browse the broader healing peptide range.
Specifications
| Property | Value |
|---|---|
| Compound | ARA-290 (Cibinetide, sequence QEQLERALNSS, a Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser 11-residue helix B-derived peptide) |
| Class | Synthetic erythropoietin-derived peptide; innate repair receptor (IRR) agonist research compound |
| Amino-acid count | 11 |
| Molecular weight | approximately 1257 g/mol |
| Supplied form | Lyophilised powder, sealed vial |
| Strength | 16 mg per vial |
| Purity | greater than 99 percent (HPLC verified) |
| Storage | 2 to 8 degrees Celsius lyophilised; minus 20 degrees Celsius long-term |
For paired research with other tissue-repair peptides, see BPC-157 5mg or TB-500 Fragment 17-23 10mg.
Reconstitution and Handling
The lyophilised vial reconstitutes with bacteriostatic water at the working concentration set by the principal investigator. Aliquoting reconstituted stock for single-use frozen storage is the standard preclinical handling practice cited in peptide-research literature.
Quality and Shipping
Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation. A Certificate of Analysis accompanies every order. Material is filled in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in temperature-monitored insulated packaging via overnight or two-day courier.
For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.
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